Integrate Analysis System IAS

IAS peut automatiser les processus manuels du début à la fin de la R&D.

IAS is not a replacement for every point tool. It is a web-based workflow layer that brings fragmented research data, analysis procedures, review records, and report creation into the same context.

  • Absorb format differences
  • Standardize analysis steps
  • Support collaborative review
Experiment-level integrationConnect imaging, NGS, flow, mass-spec, and molecular structure into one research decision.

IAS est une couche de workflow entre outils spécialisés et LIMS

IAS ne remplace pas les outils propres à chaque modalité. Il relie données d'expérience, analyse, revue et reporting dans une même surface de décision.

  1. Connect

    Regrouper les sorties d'essais

    Organise par expérience l'imagerie, la cytométrie, la génomique, la spectrométrie de masse et les structures moléculaires.

  2. Analyze

    Analyser dans un même environnement

    Traite les méthodes propres à chaque modalité dans le même espace de travail et réduit les passages manuels.

  3. Link

    Relier les preuves croisées

    Connecte les résultats de plusieurs essais à une même décision de recherche pour accélérer comparaison et interprétation.

  4. Govern

    Produire une sortie révisable

    Relie historique d'analyse, vérifications et reporting afin de soutenir des résultats finaux reproductibles.

Réinjecter les objectifs de découverte dans le plan expérimental

IAS ne se limite pas à afficher les résultats. Il structure composés cibles, candidats médicaments, hypothèses, métriques et conditions suivantes pour alimenter simulation et plans humides.

Au-delà de l'analyse, de l'interprétation et des rapports, IAS améliore la qualité du design expérimental et raccourcit le cycle entre découverte de candidats et validation humide.

Target

Repartir des composés cibles et candidats

Relie contexte pathologique, données existantes, imagerie, omiques et indicateurs structuraux pour définir efficacité, toxicité et mécanismes à explorer.

Plan

Alimenter simulation et conception d'expérience

Réinjecte conditions prometteuses, groupes de comparaison et paramètres de mesure dans la revue in silico ou le prochain plan expérimental.

Reduce

Alléger le travail de laboratoire humide

Écarte plus tôt les conditions moins prometteuses et concentre expériences, vérifications et revues sur les hypothèses utiles.

NEW FEATURE

Now supports ChatGPT and LifeAnalytics' proprietary generative AI app

Helping researchers summarize, interpret, and draft reports from complex analysis results through natural language instructions.

LifeAnalytics IAS now supports ChatGPT and LifeAnalytics' proprietary generative AI application. Using research data, analysis history, experiment records, analysis summaries, and report context, IAS helps researchers summarize, interpret, create reports, and draft scientific manuscripts from complex life science analysis results.

IAS supports multiple analysis areas including image analysis, gene analysis, flow cytometry, mass spectrometry, molecular structure analysis, spatial multi-layer multi-omics analysis, and integrated analysis.

  • Summarize and interpret results using natural language
  • Organize multiple types of life science analysis data
  • Support report creation and manuscript draft preparation
Screen image introducing ChatGPT support for LifeAnalytics IAS

Mise en œuvre de cinq méthodes représentatives de R&D et de l'analyse intégrée

IAS gère dans le cloud les données d'imagerie, cytométrie en flux, séquençage nouvelle génération, structure moléculaire et spectrométrie de masse.

IAS analysis capabilities

Genome Analysis

Visualization, alignment, assembly, and annotation of DNA and protein sequences.

Mass Spectrometry

Acquisition, processing, and analysis of mass spectrometry data, including metabolomics.

Molecular Structure Analysis

High-accuracy prediction of 3D protein structure from amino acid sequences.

Integrated Analysis

AI-assisted discussion reports based on individual analysis results.

Imaging

Image analysis for cells and tissue sections, including 3D, Timelapse, HCS, and pathology.

Flow Cytometry

Flow cytometry analysis such as SPADE, U-MAP, and dot plots.

IAS specification details

IAS Specifications: Analysis Modes, AI Models, and Support Functions

Handle imaging, flow cytometry, genomics, mass spectrometry, molecular structure, and integrated analysis in one research workbench.

IAS is not a single image-analysis application or a collection of isolated point tools. It brings imaging, flow cytometry, genomics, mass spectrometry, molecular structure analysis, integrated analysis, and data management into one research workbench experience.

IAS AI output does not guarantee clinical diagnosis. Interpretation of pathology images, medical images, genomics, molecular structure, and mass-spec results should be combined with specialist review, raw-data inspection, standard methods, and external validation.

Workflow diagram showing the full IAS analysis-mode overviewWorkflow diagram

Analysis mode cards

Each card summarizes inputs, outputs, and review points at a practical evaluation level.

Diagram showing IAS analysis mode card structure

Imaging / DL-ML

Target data
Microscopy, pathology, cell, materials, animal time-series, and spatial omics images
Representative input
Microscopy, WSI, CT/MRI-like images, timelapse, 3D volume, spatial omics images
Main output
Segmentation, ROI analysis, tracking, quantification tables, pathology-support reports
Review points
Image quality, ROI settings, mask accuracy, positivity criteria, specialist review

FlowCyto

Target data
Flow cytometry and spectral cytometry
Representative input
FCS, panel metadata, compensation matrix, gate definitions
Main output
Compensation, QC, manual gates, clustering, UMAP/t-SNE, statistics
Review points
Compensation, channel names, QC exclusion rules, gate hierarchy, threshold history

Genomics

Target data
Sequence analysis, NGS, single-cell, CRISPR, multi-omics
Representative input
FASTA, FASTQ, BAM, VCF, H5AD, tabular data
Main output
QC, alignment, variants, single-cell clusters, annotations, reports
Review points
Genome build, QC, depth, population frequency, reference data, batch correction

MassSpec

Target data
MS, MSI, proteomics, metabolomics, lipidomics, DIA, targeted quant
Representative input
raw, mzML, mgf, ms2, wiff, peak tables, identification tables, quant tables
Main output
Peak detection, identification, quantification, database matching, MSI spatial analysis
Review points
QC, blank, batch correction, FDR, standards, retention time, MS/MS evidence

Molecular Structure

Target data
Structure prediction, docking, molecular dynamics, function inference
Representative input
Sequences, PDB, mmCIF, ligands, complexes, conditions
Main output
Predicted and public structures, docking candidates, MD analysis, validation reports
Review points
Confidence, pLDDT/PAE, protonation, box, charge, force field, experimental structures

Integrate

Target data
Cross-mode integration and decision support
Representative input
Mode result tables, HDF5, JSON, CSV, sample IDs
Main output
ID mapping, statistical integration, cross-modal relations, Gen Report
Review points
Sample ID mapping, missingness, units, batches, correlation versus causation

DB Manage / Sample DB

Target data
Data management, metadata, experiment history
Representative input
Uploaded files, experiment names, sample tags, analysis history
Main output
Input history, file references, mode estimation, re-analysis paths
Review points
Sample ID consistency, history, auditability, re-analysis readiness

Analysis-mode details and review points

Long model inventories are grouped by purpose so readers can see how each model is used and what should be checked before interpreting outputs.

Imaging and DL/ML model useMore details

IAS imaging modes cover Tissue, Cell, Material, Semicon, Animal, and ML workflows so teams can choose models by purpose.

Tissue

TissueNet, Foxp3 Spatial, Foxp3 DAB Spatial, Ki67-Br, Pathology, CT/MRI Segment, Spatial Omics, TissueNT2, Thyroid, and Lymph support tissue segmentation, ROI quantification, positivity review, spatial distribution, and multi-channel statistics.

Cell

Cyto, Cyto2, SAM, 2Dtracker, 3Dtimelapse, Nuclei, Nucleus01, Confluency, CM-CellCycle, LiveCell, CP, CPx, TN1-3, LC1-4, Single Cell Protein, 3DVD, LFcell02, and CellPaintingV3 support cell segmentation, tracking, morphology profiling, localization, and state review.

Material / Semicon / Animal / ML

Pore Analysis, Layer, Microridge, Mfiber1, Mfiber2, Wafer, Mouse Dynamics Tracking, and Pixel Classification support pore, layer, ridge, fiber, wafer, animal motion, and user-defined pixel-classification reviews.

Diagram grouping IAS imaging model families by use case
Pathology mode: ROI editing, visual similarity, and finding-candidate supportMore details

Pathology mode combines local pathology processing, ROI editing, vision-language assistance, visual similarity, and nuclei/cell segmentation support.

WSI / ROI

OpenSlide, tifffile, OpenCV, and LAB/HSV/RGB Magic Wand support tissue masks, tile heatmaps, overlays, and color-space ROI editing.

AI support

Qwen2.5-VL + LoRA assist, ResNet152 visual similarity, and DeepLIIF biomarker support help generate descriptions, hypotheses, similar-image candidates, and biomarker-support summaries.

Segmentation

checkpoint-gated tumor segmentation, StarDist H&E nuclei, Cellpose-SAM service, and InstanSeg service provide candidate segmentation for tumor regions, nuclei, and cells.

This is not a diagnostic function. Outputs are research and review support for specialist-led pathology review.

Diagram showing pathology mode support functions and review premise
FlowCyto: compensation, QC, gates, clustering, and statistics in one flowMore details

IAS connects FCS input, compensation, QC, gates, embedding, clustering, statistics, and reporting.

Compensation / QC

Compensation, spectral unmixing, PeacoQC, DataQC, doublet checks, and margin checks help review spillover, spectral overlap, abnormal events, flow-rate drift, doublets, and margin events.

Gate / Embedding

Gate editor, Boolean gates, UMAP, t-SNE, opt-SNE, and viSNE help preserve manual thresholds and inspect high-dimensional cytometry data.

Cluster / Statistics

FlowSOM, SPADE, CITRUS, population statistics, and marker summaries support population comparison, MFI review, figures, and reports.

Embeddings are visualizations; interpretation should be checked against marker expression and manual gates.

Workflow diagram from FCS input to FlowCyto statistics and report
Genomics: sequences, NGS, single-cell, CRISPR, and Multi-OmicsMore details

IAS organizes sequence similarity, alignment, variants, single-cell analysis, reference mapping, and multi-omics evidence by experiment.

Sequence / Variant

BLAST, MSA, Phylogeny, CRISPR, QC & Alignment, Variant Calling, Joint Genotyping, and Annotation connect sequence review to variant and annotation review.

Browser / Single-cell

Genome Browser and Single-cell Async support genomic-region inspection, variants, gene models, normalization, HVG, PCA, clustering, UMAP, and marker detection.

Advanced / Multi-Omics

Harmony, scGPT, cell annotation capability checks, and Multi-Omics connect batch correction, reference mapping, cell-type annotation candidates, expression, variants, phenotypes, and other modes.

Check genome build, QC, depth, population frequency, labeled references, batch effects, missingness, and unit alignment.

Diagram connecting genomics results with other modes by sample ID
MassSpec: peak detection, identification, quantification, MSI, and spectral similarityMore details

IAS connects raw/mzML/mgf/wiff inputs to peak features, identification, quantification, QC, database matching, reports, and multi-omics.

Metabolomics / Lipidomics

MS-DIAL, XCMS, MZmine, MS-FINDER, MS-CleanR, LipidSearch, and LipidBlast outputs are organized for candidate review and quantification.

Proteomics / MSI

MaxQuant, Proteome Discoverer, FragPipe, Mascot, Byonic, Spectronaut, DIA-NN, OpenSWATH, Prosit, SCiLS Lab, Cardinal, MSiReader, METASPACE, and OpenMSI outputs can be reviewed as part of the same workflow.

Target / AI / Multi-omics

MRM/SRM/PRM, MRMProbs, DeepNovo, Spec2Vec, MS2DeepScore, AlphaPept, mixOmics, MOFA(+), DIABLO, and OmicsNet outputs can be tied back to research decisions.

AI candidates should be verified with database matching, standards, MS/MS evidence, FDR, QC, blanks, and batch correction.

Workflow diagram from mass-spec raw input to peak review and report
Molecular Structure: structure prediction, docking, MD, and validation reportsMore details

IAS helps review the path from Sequence/PDB/Ligand to structure prediction, docking, MD, validation, and reports.

Structure prediction

Monomer and complex structure prediction, public structure retrieval, and pLDDT/PAE review are handled as review inputs.

Docking / MD

GNINA, AutoDock-family, LightDock path, OpenMM, and mdtraj support binding-pose candidates, scores, binding-site review, RMSD/RMSF, interactions, and solvent-condition review.

Validation / Extensions

Validation quality checks, reports, function annotation, spectrum prediction, knowledge graph, QM, and FEP scaffolds help organize quality and extension candidates.

Check confidence, pLDDT/PAE, protonation, box, charge, ligand preparation, force field, solvent, temperature, and simulation length.

Workflow diagram from sequence and ligand input to molecular validation report
Integrate / DB Manage: sample IDs, experiment history, and evidence maturityMore details

IAS connects imaging, genomics, mass spec, flow cytometry, molecular structure, and reports around a consistent sample ID.

Mapping

sample ID and provenance mapping connect sample IDs, experiments, files, and preprocessing history across modes.

Statistics / Cross-modal

compute-statistics, random-effects meta-analysis, and cross-modal review connect effect sizes, confidence intervals, heterogeneity, imaging features, gene expression, metabolites, and population ratios.

Report / DB

Gen Report, report history, evidence maturity, DB Manage, and Sample DB help preserve report context, input history, file references, mode estimation, and re-analysis paths.

For clinical research support, keeping the same sample ID across Imaging, Genomics, MassSpec, and FlowCyto is critical.

Hub diagram connecting analysis modes around sample ID
Support functions: Support Chat, Patho Chat, and Q&A HelpMore details

Support functions reduce uncertainty during analysis by connecting operation guidance, knowledge search, ROI questions, and help dialogs.

Support Chat

Support Chat connects operation guidance, inquiry handoff, knowledge search, and AI-answer support for Imaging, Genomics, FlowCyto, Molecular, MassSpec, and Integrate.

Patho Chat / ROI Pathology Chat

Patho Chat combines ROI crops, feature extraction, similarity candidates, and Qwen-family LLM support to provide finding candidates, differential candidates, and suggested checks under pathology-specialist review.

Q&A / Help

Q&A icons and Help screens reduce operation mistakes through tooltips, Quick Start, Help dialogs, shortcut explanations, and Support Chat / Patho Chat visibility controls.

Patho Chat does not replace pathology review. Outputs are confirmation support and hypothesis-generation support for selected ROIs.

Illustration connecting analysis screens to Support Chat and Patho Chat assistance

Five points to check during IAS evaluation

  1. Input typeWhether images, FCS, FASTQ/BAM/VCF/H5AD, mzML/raw, PDB/mmCIF, or integrated tables fit the target mode.
  2. Model or engine purposeWhat segmentation, tracking, annotation, clustering, docking, MD, or spectral matching output actually means.
  3. Output unitWhether the output is ROI, cell, nucleus, population, variant, peptide/protein, metabolite/lipid, structure, or cross-sample statistics.
  4. Validation itemsWhether QC, thresholds, confidence, FDR, reference databases, external standards, and specialist review remain visible.
  5. Support functionsWhether Support Chat, Patho Chat, and Q&A / Help give the right workflow guidance in context.

Check IAS fit with your own data

Your target data, analysis problem, and evaluation timing do not need to be fully organized. We can review the appropriate analysis modes and implementation path with you.

Demo consultation

Couverture complète des méthodes analytiques en recherche fondamentale

Les méthodes d'analyse sont unifiées pour permettre aux chercheurs de travailler dans un même environnement reproductible.

Couverture complète des méthodes analytiques en recherche fondamentale

Développement additionnel d'IA propriétaire et de fonctions

Nous ajoutons des IA et fonctions d'analyse adaptées à vos objectifs pour automatiser l'ensemble du processus de recherche.

Développement additionnel d'IA propriétaire et de fonctions

Fonctionnalités de la plateforme IAS

Coordonner et gérer tout le laboratoire

Coordonner et gérer tout le laboratoire

Gérez données, analyses et rapports dans un seul système web.

Système web complet

Système web complet

Utilisez la même plateforme en collaboration et à distance sans installation locale.

Support 24 h via chat

Support 24 h via chat

Fluidifie les questions et vérifications pendant l'analyse.

Gestion robuste des données

Gestion robuste des données

Conçu pour la gestion des données, la prévention des fuites et les besoins réglementaires.

Suggestions par IA générative

Suggestions par IA générative

Aide à repérer les points importants dans les images et résultats.

Plus de 400 formats pris en charge

Plus de 400 formats pris en charge

Soutient l'intégration des formats variés utilisés en recherche.

Retours utilisateurs

Travail d'analyse standardisé

Les procédures spécialisées se partagent plus facilement et améliorent la reproductibilité en collaboration à distance.

Efficacité à l'échelle du laboratoire

La gestion centralisée de multiples formats réduit le temps d'analyse et de reporting.

Plus de 400 formats pris en charge

Prend en charge de nombreux formats uniques d'image et d'analyse, et fonctionne comme système intégré d'analyse de données.

Exemples de formats de données pris en charge

Microscopy and bioimagingRepresentative research image formats from OME-TIFF, confocal, slide scanners, and electron microscopy.
  • .ome.tiff
  • .ome.tif
  • .ome.xml
  • .czi
  • .lsm
  • .lif
  • .nd2
  • .oib
  • .oif
  • .oir
  • .vsi
  • .svs
  • .ndpi
  • .qptiff
  • .dm3
  • .dm4
  • .mrc
  • .mrcs
General image, video, and documentsCommon image, video, tabular, HTML, and XML files used before and after analysis.
  • .tif
  • .tiff
  • .png
  • .jpg
  • .bmp
  • .gif
  • .avi
  • .mov
  • .csv
  • .txt
  • .xml
  • .html
  • .h5
  • .hdf
NGS and genomicsSequence, alignment, variant, and array-related data organized by experiment.
  • fastq
  • fasta
  • bam
  • vcf
  • cel
  • chp
  • arr
  • idat
Flow cytometry and qPCRCell population analysis, digital PCR, and instrument outputs with experiment metadata.
  • stilla
  • rdml
  • .pnl
  • .rdpnl
  • .exp
  • .xml
  • .csv
Mass spectrometry and chromatographyRaw data, converted data, and vendor formats used around mass spectrometry analysis.
  • mzml
  • raw
  • wiff
  • d
  • .spc
  • .std
  • .dat
  • .res
Molecular structure, materials, and QCMolecular structure, materials observation, semiconductor, and quality-control inspection outputs.
  • .cif
  • sdf
  • qip
  • eds
  • lmd
  • .sxm
  • .afm
  • .stp
  • .map
  • .rec

Contactez-nous également pour les formats qui ne figurent pas dans cette liste.

Compatible avec gestion des données, prévention des fuites et réglementation

Compatible avec gestion des données, prévention des fuites et réglementation

Soutient une gestion tenant compte de 21 CFR Part 11 et d'autres exigences.

Outils de visualisation riches

Outils de visualisation riches

Aident à inspecter intuitivement les résultats d'analyse.

Rédaction de rapports et articles

Rédaction de rapports et articles

Aide à produire rapports et brouillons de manuscrits à partir des résultats.

Automatisation complète du laboratoire

Automatisation complète du laboratoire

Relie analyse, gestion et reporting pour améliorer tout le flux du laboratoire.

Exemples d'applications

Each card separates the input data, the outputs IAS organizes, and the research decision it supports. Flow Cytometry, NGS, Molecular Structure, and MassSpec are treated as first-class analysis modes alongside Imaging.

Inférence d'effets et de toxicités inconnus

Inférence d'effets et de toxicités inconnus

Pour découverte de médicaments, toxicité et exploration

L'IA infère des effets et toxicités inconnus en reliant des paramètres spécifiques et des informations de maladie à partir de plus de 1000 paramètres, plus de 100 000 cellules et l'extraction d'organites.

Inputs
HCS images, Cell Painting images, tissue or cell images, treatment conditions
Outputs
Morphology features, clusters, regions of interest, compound and disease similarity
Decision use
Prioritize candidate compounds, flag toxicity signals, and plan follow-up conditions
Production cellulaire

Production cellulaire

Pour thérapie génique et cellules iPS

IAS prend en charge les étapes nécessitant une décision visuelle d'acceptation depuis la R&D jusqu'à la production et au contrôle qualité des Stem Cells et cellules iPS.

Inputs
FCS files, panel definitions, gating conditions, sample groups
Outputs
Population ratios, gate-level comparisons, abnormal population candidates, QC summaries
Decision use
Review cell-production lots, compare immune response, and catch quality drift earlier
Suivi dynamique et analyse du comportement de groupe des petits animaux

Suivi dynamique et analyse du comportement de groupe des petits animaux

Pour souris et modèles similaires

Suit le corps et les membres de petits animaux et analyse le comportement de groupe sans être affecté par le jour, la nuit ou les différences de pelage.

Inputs
FASTQ/BAM/VCF files, expression tables, sample attributes, phenotype context
Outputs
Variant candidates, expression changes, annotations, cross-sample review views
Decision use
Shortlist genes, interpret group differences, and choose follow-up validation targets
Molecular Structure: 3D structure comparison

Molecular Structure: 3D structure comparison

Proteins, materials, and structural evaluation

Manage 3D structures, segmented regions, features, and candidate models so structural differences and regions of interest are easier to compare.

Inputs
PDB/mmCIF files, predicted structures, binding sites, candidate molecules or materials
Outputs
Structure overlays, difference regions, binding-site notes, comparison reports
Decision use
Review structure hypotheses, compare candidates, and prepare docking or materials evaluation
MassSpec: Spectral peak interpretation

MassSpec: Spectral peak interpretation

Metabolites, quality evaluation, and component comparison

Manage spectra, peaks, sample conditions, and comparison groups to support component review, quality differences, and reporting.

Inputs
mzML/mzXML files, peak lists, sample conditions, comparison groups or lots
Outputs
Peak candidates, component comparisons, quality differences, report annotations
Decision use
Confirm metabolite candidates, understand lot differences, and organize quality evidence
Système d'analyse intégrée IAS - LifeAnalytics