Integrate Analysis System IAS

Connect imaging, NGS, flow cytometry, mass spectrometry, and molecular structure data by experiment.

IAS is not a replacement for every point tool. It is a web-based workflow layer that brings fragmented research data, analysis procedures, review records, and report creation into the same context.

  • Absorb format differences
  • Standardize analysis steps
  • Support collaborative review
Experiment-level integrationConnect imaging, NGS, flow, mass-spec, and molecular structure into one research decision.

IAS is a workflow layer between point tools and LIMS

IAS does not replace modality-specific tools. It connects experiment-level data, analysis, review, and reporting into one decision surface.

  1. Connect

    Bundle assay outputs

    Organize imaging, flow, genomics, mass spectrometry, and molecular structure outputs by experiment.

  2. Analyze

    Work in one environment

    Handle modality-specific analysis methods in the same workspace and reduce manual handoffs.

  3. Link

    Connect cross-assay evidence

    Tie multiple assay results into one research decision so comparison and interpretation move faster.

  4. Govern

    Create reviewable output

    Carry analysis history, checks, and report creation toward reproducible final outputs.

Feed discovery goals back into simulation and wet-lab planning

IAS organizes target compounds, candidate drugs, hypotheses, evaluation metrics, and next conditions so analysis results can shape simulation and experimental planning before the next run.

Beyond improving analysis accuracy, interpretation, and reporting efficiency, IAS raises experiment-design quality and shortens the research cycle from candidate discovery to wet validation.

Target

Work backward from target compounds and candidates

Connect disease context, existing data, imaging, omics, and structural indicators to define the efficacy, toxicity, and mechanism conditions to explore.

Plan

Reflect findings in simulation and experiment design

Feed promising conditions, comparison groups, and measurement parameters into the next in silico review or wet-lab plan so trial order becomes clearer.

Reduce

Reduce wet-lab research effort

Screen out lower-promise conditions earlier and focus experiments, checks, and reviews where they matter, reducing effort in both analysis work and wet-lab research.

NEW FEATURE

Now supports ChatGPT and LifeAnalytics' proprietary generative AI app

Helping researchers summarize, interpret, and draft reports from complex analysis results through natural language instructions.

LifeAnalytics IAS now supports ChatGPT and LifeAnalytics' proprietary generative AI application. Using research data, analysis history, experiment records, analysis summaries, and report context, IAS helps researchers summarize, interpret, create reports, and draft scientific manuscripts from complex life science analysis results.

IAS supports multiple analysis areas including image analysis, gene analysis, flow cytometry, mass spectrometry, molecular structure analysis, spatial multi-layer multi-omics analysis, and integrated analysis.

  • Summarize and interpret results using natural language
  • Organize multiple types of life science analysis data
  • Support report creation and manuscript draft preparation
Screen image introducing ChatGPT support for LifeAnalytics IAS

Implementation of five representative methodologies used in research and development and integrated analysis

IAS centrally manages representative research data such as image analysis, flow cytometry, next generation sequencing, molecular structure, and mass spectrometry in the cloud.

IAS analysis capabilities

Genome Analysis

Visualization, alignment, assembly, and annotation of DNA and protein sequences.

Mass Spectrometry

Acquisition, processing, and analysis of mass spectrometry data, including metabolomics.

Molecular Structure Analysis

High-accuracy prediction of 3D protein structure from amino acid sequences.

Integrated Analysis

AI-assisted discussion reports based on individual analysis results.

Imaging

Image analysis for cells and tissue sections, including 3D, Timelapse, HCS, and pathology.

Flow Cytometry

Flow cytometry analysis such as SPADE, U-MAP, and dot plots.

IAS specification details

IAS Specifications: Analysis Modes, AI Models, and Support Functions

Handle imaging, flow cytometry, genomics, mass spectrometry, molecular structure, and integrated analysis in one research workbench.

IAS is not a single image-analysis application or a collection of isolated point tools. It brings imaging, flow cytometry, genomics, mass spectrometry, molecular structure analysis, integrated analysis, and data management into one research workbench experience.

IAS AI output does not guarantee clinical diagnosis. Interpretation of pathology images, medical images, genomics, molecular structure, and mass-spec results should be combined with specialist review, raw-data inspection, standard methods, and external validation.

Workflow diagram showing the full IAS analysis-mode overviewWorkflow diagram

Analysis mode cards

Each card summarizes inputs, outputs, and review points at a practical evaluation level.

Diagram showing IAS analysis mode card structure

Imaging / DL-ML

Target data
Microscopy, pathology, cell, materials, animal time-series, and spatial omics images
Representative input
Microscopy, WSI, CT/MRI-like images, timelapse, 3D volume, spatial omics images
Main output
Segmentation, ROI analysis, tracking, quantification tables, pathology-support reports
Review points
Image quality, ROI settings, mask accuracy, positivity criteria, specialist review

FlowCyto

Target data
Flow cytometry and spectral cytometry
Representative input
FCS, panel metadata, compensation matrix, gate definitions
Main output
Compensation, QC, manual gates, clustering, UMAP/t-SNE, statistics
Review points
Compensation, channel names, QC exclusion rules, gate hierarchy, threshold history

Genomics

Target data
Sequence analysis, NGS, single-cell, CRISPR, multi-omics
Representative input
FASTA, FASTQ, BAM, VCF, H5AD, tabular data
Main output
QC, alignment, variants, single-cell clusters, annotations, reports
Review points
Genome build, QC, depth, population frequency, reference data, batch correction

MassSpec

Target data
MS, MSI, proteomics, metabolomics, lipidomics, DIA, targeted quant
Representative input
raw, mzML, mgf, ms2, wiff, peak tables, identification tables, quant tables
Main output
Peak detection, identification, quantification, database matching, MSI spatial analysis
Review points
QC, blank, batch correction, FDR, standards, retention time, MS/MS evidence

Molecular Structure

Target data
Structure prediction, docking, molecular dynamics, function inference
Representative input
Sequences, PDB, mmCIF, ligands, complexes, conditions
Main output
Predicted and public structures, docking candidates, MD analysis, validation reports
Review points
Confidence, pLDDT/PAE, protonation, box, charge, force field, experimental structures

Integrate

Target data
Cross-mode integration and decision support
Representative input
Mode result tables, HDF5, JSON, CSV, sample IDs
Main output
ID mapping, statistical integration, cross-modal relations, Gen Report
Review points
Sample ID mapping, missingness, units, batches, correlation versus causation

DB Manage / Sample DB

Target data
Data management, metadata, experiment history
Representative input
Uploaded files, experiment names, sample tags, analysis history
Main output
Input history, file references, mode estimation, re-analysis paths
Review points
Sample ID consistency, history, auditability, re-analysis readiness

Analysis-mode details and review points

Long model inventories are grouped by purpose so readers can see how each model is used and what should be checked before interpreting outputs.

Imaging and DL/ML model useMore details

IAS imaging modes cover Tissue, Cell, Material, Semicon, Animal, and ML workflows so teams can choose models by purpose.

Tissue

TissueNet, Foxp3 Spatial, Foxp3 DAB Spatial, Ki67-Br, Pathology, CT/MRI Segment, Spatial Omics, TissueNT2, Thyroid, and Lymph support tissue segmentation, ROI quantification, positivity review, spatial distribution, and multi-channel statistics.

Cell

Cyto, Cyto2, SAM, 2Dtracker, 3Dtimelapse, Nuclei, Nucleus01, Confluency, CM-CellCycle, LiveCell, CP, CPx, TN1-3, LC1-4, Single Cell Protein, 3DVD, LFcell02, and CellPaintingV3 support cell segmentation, tracking, morphology profiling, localization, and state review.

Material / Semicon / Animal / ML

Pore Analysis, Layer, Microridge, Mfiber1, Mfiber2, Wafer, Mouse Dynamics Tracking, and Pixel Classification support pore, layer, ridge, fiber, wafer, animal motion, and user-defined pixel-classification reviews.

Diagram grouping IAS imaging model families by use case
Pathology mode: ROI editing, visual similarity, and finding-candidate supportMore details

Pathology mode combines local pathology processing, ROI editing, vision-language assistance, visual similarity, and nuclei/cell segmentation support.

WSI / ROI

OpenSlide, tifffile, OpenCV, and LAB/HSV/RGB Magic Wand support tissue masks, tile heatmaps, overlays, and color-space ROI editing.

AI support

Qwen2.5-VL + LoRA assist, ResNet152 visual similarity, and DeepLIIF biomarker support help generate descriptions, hypotheses, similar-image candidates, and biomarker-support summaries.

Segmentation

checkpoint-gated tumor segmentation, StarDist H&E nuclei, Cellpose-SAM service, and InstanSeg service provide candidate segmentation for tumor regions, nuclei, and cells.

This is not a diagnostic function. Outputs are research and review support for specialist-led pathology review.

Diagram showing pathology mode support functions and review premise
FlowCyto: compensation, QC, gates, clustering, and statistics in one flowMore details

IAS connects FCS input, compensation, QC, gates, embedding, clustering, statistics, and reporting.

Compensation / QC

Compensation, spectral unmixing, PeacoQC, DataQC, doublet checks, and margin checks help review spillover, spectral overlap, abnormal events, flow-rate drift, doublets, and margin events.

Gate / Embedding

Gate editor, Boolean gates, UMAP, t-SNE, opt-SNE, and viSNE help preserve manual thresholds and inspect high-dimensional cytometry data.

Cluster / Statistics

FlowSOM, SPADE, CITRUS, population statistics, and marker summaries support population comparison, MFI review, figures, and reports.

Embeddings are visualizations; interpretation should be checked against marker expression and manual gates.

Workflow diagram from FCS input to FlowCyto statistics and report
Genomics: sequences, NGS, single-cell, CRISPR, and Multi-OmicsMore details

IAS organizes sequence similarity, alignment, variants, single-cell analysis, reference mapping, and multi-omics evidence by experiment.

Sequence / Variant

BLAST, MSA, Phylogeny, CRISPR, QC & Alignment, Variant Calling, Joint Genotyping, and Annotation connect sequence review to variant and annotation review.

Browser / Single-cell

Genome Browser and Single-cell Async support genomic-region inspection, variants, gene models, normalization, HVG, PCA, clustering, UMAP, and marker detection.

Advanced / Multi-Omics

Harmony, scGPT, cell annotation capability checks, and Multi-Omics connect batch correction, reference mapping, cell-type annotation candidates, expression, variants, phenotypes, and other modes.

Check genome build, QC, depth, population frequency, labeled references, batch effects, missingness, and unit alignment.

Diagram connecting genomics results with other modes by sample ID
MassSpec: peak detection, identification, quantification, MSI, and spectral similarityMore details

IAS connects raw/mzML/mgf/wiff inputs to peak features, identification, quantification, QC, database matching, reports, and multi-omics.

Metabolomics / Lipidomics

MS-DIAL, XCMS, MZmine, MS-FINDER, MS-CleanR, LipidSearch, and LipidBlast outputs are organized for candidate review and quantification.

Proteomics / MSI

MaxQuant, Proteome Discoverer, FragPipe, Mascot, Byonic, Spectronaut, DIA-NN, OpenSWATH, Prosit, SCiLS Lab, Cardinal, MSiReader, METASPACE, and OpenMSI outputs can be reviewed as part of the same workflow.

Target / AI / Multi-omics

MRM/SRM/PRM, MRMProbs, DeepNovo, Spec2Vec, MS2DeepScore, AlphaPept, mixOmics, MOFA(+), DIABLO, and OmicsNet outputs can be tied back to research decisions.

AI candidates should be verified with database matching, standards, MS/MS evidence, FDR, QC, blanks, and batch correction.

Workflow diagram from mass-spec raw input to peak review and report
Molecular Structure: structure prediction, docking, MD, and validation reportsMore details

IAS helps review the path from Sequence/PDB/Ligand to structure prediction, docking, MD, validation, and reports.

Structure prediction

Monomer and complex structure prediction, public structure retrieval, and pLDDT/PAE review are handled as review inputs.

Docking / MD

GNINA, AutoDock-family, LightDock path, OpenMM, and mdtraj support binding-pose candidates, scores, binding-site review, RMSD/RMSF, interactions, and solvent-condition review.

Validation / Extensions

Validation quality checks, reports, function annotation, spectrum prediction, knowledge graph, QM, and FEP scaffolds help organize quality and extension candidates.

Check confidence, pLDDT/PAE, protonation, box, charge, ligand preparation, force field, solvent, temperature, and simulation length.

Workflow diagram from sequence and ligand input to molecular validation report
Integrate / DB Manage: sample IDs, experiment history, and evidence maturityMore details

IAS connects imaging, genomics, mass spec, flow cytometry, molecular structure, and reports around a consistent sample ID.

Mapping

sample ID and provenance mapping connect sample IDs, experiments, files, and preprocessing history across modes.

Statistics / Cross-modal

compute-statistics, random-effects meta-analysis, and cross-modal review connect effect sizes, confidence intervals, heterogeneity, imaging features, gene expression, metabolites, and population ratios.

Report / DB

Gen Report, report history, evidence maturity, DB Manage, and Sample DB help preserve report context, input history, file references, mode estimation, and re-analysis paths.

For clinical research support, keeping the same sample ID across Imaging, Genomics, MassSpec, and FlowCyto is critical.

Hub diagram connecting analysis modes around sample ID
Support functions: Support Chat, Patho Chat, and Q&A HelpMore details

Support functions reduce uncertainty during analysis by connecting operation guidance, knowledge search, ROI questions, and help dialogs.

Support Chat

Support Chat connects operation guidance, inquiry handoff, knowledge search, and AI-answer support for Imaging, Genomics, FlowCyto, Molecular, MassSpec, and Integrate.

Patho Chat / ROI Pathology Chat

Patho Chat combines ROI crops, feature extraction, similarity candidates, and Qwen-family LLM support to provide finding candidates, differential candidates, and suggested checks under pathology-specialist review.

Q&A / Help

Q&A icons and Help screens reduce operation mistakes through tooltips, Quick Start, Help dialogs, shortcut explanations, and Support Chat / Patho Chat visibility controls.

Patho Chat does not replace pathology review. Outputs are confirmation support and hypothesis-generation support for selected ROIs.

Illustration connecting analysis screens to Support Chat and Patho Chat assistance

Five points to check during IAS evaluation

  1. Input typeWhether images, FCS, FASTQ/BAM/VCF/H5AD, mzML/raw, PDB/mmCIF, or integrated tables fit the target mode.
  2. Model or engine purposeWhat segmentation, tracking, annotation, clustering, docking, MD, or spectral matching output actually means.
  3. Output unitWhether the output is ROI, cell, nucleus, population, variant, peptide/protein, metabolite/lipid, structure, or cross-sample statistics.
  4. Validation itemsWhether QC, thresholds, confidence, FDR, reference databases, external standards, and specialist review remain visible.
  5. Support functionsWhether Support Chat, Patho Chat, and Q&A / Help give the right workflow guidance in context.

Check IAS fit with your own data

Your target data, analysis problem, and evaluation timing do not need to be fully organized. We can review the appropriate analysis modes and implementation path with you.

Demo consultation

Comprehensive coverage of analytical methods in fundamental research

Analytical methods for fundamental research are unified so researchers can work in the same environment with reproducible workflows.

Comprehensive coverage of analytical methods in fundamental research

Additional development of proprietary AI and features

We support additional proprietary AI and analysis features tailored to your goals, helping automate the entire research process.

Additional development of proprietary AI and features

Features of the IAS Platform

Coordinate and manage the entire lab

Coordinate and manage the entire lab

Manage data, analysis, and reports in one web system.

Complete Web System

Complete Web System

Use the same analysis platform in collaborative and remote environments without local installation.

24-hour support via chat function

24-hour support via chat function

Smoothly proceed with questions and checks during analysis work.

Robust Data Management

Robust Data Management

Designed for compatibility with data management, leak prevention, and regulatory needs.

Generative AI Suggestions for Unique Selling Points

Generative AI Suggestions for Unique Selling Points

Support discovery of notable points from images and analysis results.

Organized support for many research formats

Organized support for many research formats

Supports integration of many data formats used in research settings.

User Feedback

Standardized analysis work

Specialized analysis procedures can be shared more easily, improving reproducibility in remote collaboration.

Efficiency across the lab

Central management of multiple data formats reduces the time required for analysis and reporting.

Explore 400+ supported formats by category

Instead of a long extension list, representative formats are grouped by research workflow and data type. For formats not shown here, share example files, instrument names, and desired outputs.

Representative data formats by category

Microscopy and bioimagingRepresentative research image formats from OME-TIFF, confocal, slide scanners, and electron microscopy.
  • .ome.tiff
  • .ome.tif
  • .ome.xml
  • .czi
  • .lsm
  • .lif
  • .nd2
  • .oib
  • .oif
  • .oir
  • .vsi
  • .svs
  • .ndpi
  • .qptiff
  • .dm3
  • .dm4
  • .mrc
  • .mrcs
General image, video, and documentsCommon image, video, tabular, HTML, and XML files used before and after analysis.
  • .tif
  • .tiff
  • .png
  • .jpg
  • .bmp
  • .gif
  • .avi
  • .mov
  • .csv
  • .txt
  • .xml
  • .html
  • .h5
  • .hdf
NGS and genomicsSequence, alignment, variant, and array-related data organized by experiment.
  • fastq
  • fasta
  • bam
  • vcf
  • cel
  • chp
  • arr
  • idat
Flow cytometry and qPCRCell population analysis, digital PCR, and instrument outputs with experiment metadata.
  • stilla
  • rdml
  • .pnl
  • .rdpnl
  • .exp
  • .xml
  • .csv
Mass spectrometry and chromatographyRaw data, converted data, and vendor formats used around mass spectrometry analysis.
  • mzml
  • raw
  • wiff
  • d
  • .spc
  • .std
  • .dat
  • .res
Molecular structure, materials, and QCMolecular structure, materials observation, semiconductor, and quality-control inspection outputs.
  • .cif
  • sdf
  • qip
  • eds
  • lmd
  • .sxm
  • .afm
  • .stp
  • .map
  • .rec

Please contact us for formats not listed above.

Good Compatibility with Data Management, Leak Prevention and Regulation

Good Compatibility with Data Management, Leak Prevention and Regulation

Support data management that considers regulatory requirements such as 21 CFR Part 11.

Rich visualization tools

Rich visualization tools

Visualization tools help researchers inspect analysis results intuitively.

Drafting reports and papers

Drafting reports and papers

Support report and manuscript draft creation from analysis results.

Achieving Complete Laboratory Automation

Achieving Complete Laboratory Automation

Connect analysis, management, and reporting to improve the entire lab workflow.

Application Examples by Analysis Mode

Each card separates the input data, the outputs IAS organizes, and the research decision it supports. Flow Cytometry, NGS, Molecular Structure, and MassSpec are treated as first-class analysis modes alongside Imaging.

Imaging: Drug efficacy and toxicity inference

Imaging: Drug efficacy and toxicity inference

Image analysis and Cell Painting

Extract morphology, organelle, and cluster features from cell images and connect them with disease context and known compound tendencies.

Inputs
HCS images, Cell Painting images, tissue or cell images, treatment conditions
Outputs
Morphology features, clusters, regions of interest, compound and disease similarity
Decision use
Prioritize candidate compounds, flag toxicity signals, and plan follow-up conditions
Flow Cytometry: Cell population QC

Flow Cytometry: Cell population QC

Immune cells, cell therapy, and quality control

Organize FCS gating, population ratios, and abnormal population comparisons for cell therapy, immune analysis, and reporting workflows.

Inputs
FCS files, panel definitions, gating conditions, sample groups
Outputs
Population ratios, gate-level comparisons, abnormal population candidates, QC summaries
Decision use
Review cell-production lots, compare immune response, and catch quality drift earlier
NGS: Integrated variant and expression review

NGS: Integrated variant and expression review

Genomics, RNA-seq, and clinical research

Bring sequence outputs, variant candidates, expression changes, and sample context into a single review surface with other assay results.

Inputs
FASTQ/BAM/VCF files, expression tables, sample attributes, phenotype context
Outputs
Variant candidates, expression changes, annotations, cross-sample review views
Decision use
Shortlist genes, interpret group differences, and choose follow-up validation targets
Molecular Structure: 3D structure comparison

Molecular Structure: 3D structure comparison

Proteins, materials, and structural evaluation

Manage 3D structures, segmented regions, features, and candidate models so structural differences and regions of interest are easier to compare.

Inputs
PDB/mmCIF files, predicted structures, binding sites, candidate molecules or materials
Outputs
Structure overlays, difference regions, binding-site notes, comparison reports
Decision use
Review structure hypotheses, compare candidates, and prepare docking or materials evaluation
MassSpec: Spectral peak interpretation

MassSpec: Spectral peak interpretation

Metabolites, quality evaluation, and component comparison

Manage spectra, peaks, sample conditions, and comparison groups to support component review, quality differences, and reporting.

Inputs
mzML/mzXML files, peak lists, sample conditions, comparison groups or lots
Outputs
Peak candidates, component comparisons, quality differences, report annotations
Decision use
Confirm metabolite candidates, understand lot differences, and organize quality evidence
Integrate Analysis System IAS - LifeAnalytics